Polymorphism in the pharmaceutical industry. Rolf Hilfiker

Polymorphism in the pharmaceutical industry


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ISBN: 3527311467,9783527311460 | 433 pages | 11 Mb


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Polymorphism in the pharmaceutical industry Rolf Hilfiker
Publisher: Wiley-VCH




GlaxoSmithKline - one of the world's leading research-based pharmaceutical and healthcare companies - is committed to improving the quality of human life by enabling people to do more, feel better Read more. Polymorphism in the pharmaceutical industry. We report here the dimorphic solid-state structures of the title compound, (II) [link] . "Genetic testing is rapidly becoming affordable, and some companies have started offering tests with single nucleotide polymorphism microarrays for less than $300 per person," the researchers say. Cost-effective methods for genotyping are being developed and it would For the pharmaceutical companies, segmentation of the market may not leave room for conventional blockbusters but smaller and exclusive markets for personalized medicines would be profitable. In Polymorphism in the Pharmaceutical Industry. There are many patent issues with regards to the different polymorphs of drug molecules in the pharmaceutical industry, and a range of other industries. A letter on understanding triphasic HCV decline during treatment in the era of IL28B polymorphisms and direct acting antiviral agents via mathematical modeling, published in the Journal of Hepatology. Download Polymorphism in the pharmaceutical industry. Ten or 20 years from now, we will be sending our patients to the laboratory to characterize them in terms of genetic polymorphisms and/or to an imaging laboratory. Avoiding action has not yet widely been taken on polymorphism by the global pharmaceutical industry, so it is worth repeating the story. The knowledge of the effects of polymorphisms of genes for the enzymes is applied in drug discovery and development as well as in clinical use of drugs. Oxford ; Hilfiker, 2006 [Hilfiker, R. This is all to do with a phenomenon known as polymorphism, which is the ability for a solid to exist in more than one crystal structure. Polymorphism in the pharmaceutical industry by Rolf Hilfiker. Then based on those findings, and on the In the meantime, these companies are selling their services to pharmaceutical companies for research into new drugs to fill this soon-to-be-discovered future need – gearing up to create a new pipeline for the drug trade. Each crystal structure is called a polymorph, and each polymorph has its own set of distinct only have implications on your chocolate, but on almost anything that can crystallise. Of Health and published in Gut. In Polymorphism in Molecular Crystals.